Understanding Apraxia and Speech Delay: A Functional Medicine View of Motor Planning and Healing

As a parent, you’ve probably asked yourself: Why doesn’t my child say what they mean? Or why can they understand something, but not reliably do it?
These are often the questions that lead to the concept of apraxia—a challenge of motor planning and speech coordination rather than a lack of understanding.

Two of my favorite educators from the MAPS (Medical Academy of Pediatric Special Needs) program, Dr. Dana Johnson and Dr. Anju Usman Singh, have each contributed valuable insight into this area. Their work beautifully illustrates how both body and brain must be supported to help children overcome speech delays and motor planning challenges that may underlie apraxia.


What Is Apraxia (and How It Relates to Speech Delay)?

The word praxia comes from the Greek for doing, and “a-” means without. Apraxia describes difficulty planning and executing voluntary movements—even when comprehension and muscle strength are intact.

For many children, this shows up as speech delay or inconsistent verbal output. They may know what they want to say but can’t consistently get the words out. Others experience broader body-movement challenges that affect coordination, imitation, and daily tasks.

Apraxia is not simply a speech disorder—it’s a motor coordination issue that can influence every part of how a child expresses themselves and engages with the world.


Insights from Dr. Dana Johnson

Dr. Dana Johnson, PhD, MS, OTR/L is an occupational therapist and researcher based in Tampa, Florida. She specializes in motor planning, apraxia, and sensory-motor integration in children and adults who are non-speaking, minimally speaking, or inconsistently verbal.

Dr. Johnson’s work highlights that communication is not only cognitive—it’s motor-based. For many children with speech delay or limited expressive language, the challenge lies in the brain-body connection needed to initiate and sequence speech movements.

By supporting that connection through sensory integration, intentional movement, and motor-reliability work, she helps children build consistency and confidence in communication.

Her educational contributions through Documenting Hope and the MAPS community have helped countless clinicians and parents better understand how body-based support can unlock communication potential.


Insights from Dr. Anju Usman Singh

Dr. Anju Usman Singh, MD, FAAFP, ABIHM, FMAPS is the director of True Health Medical Center in Naperville, Illinois. A board-certified family and integrative medicine physician, she has been a pioneer in biomedical and functional approaches to autism, ADHD, apraxia, and speech delay.

Dr. Usman Singh’s work focuses on how underlying toxic load and nutritional deficiencies can interfere with neurological and motor development. Imbalances in zinc and copper, mitochondrial function, chronic infections, and environmental exposures can all impact how efficiently the brain and nervous system coordinate movement and speech.

Her research supports the idea that when the body’s detoxification, immune, and metabolic systems are overwhelmed—or when it lacks key nutrients—motor control and speech production can both be affected.


A Functional Medicine Framework for Speech and Motor Development

Through a functional medicine lens, we look at the underlying “terrain” of the body that influences brain-body communication. When speech delay or apraxia is present, there are often contributing factors that make it harder for the nervous system to function efficiently.

That exploration may include reducing toxic load from environmental chemicals, heavy metals, or infections that stress the nervous system; replenishing nutrients like zinc, magnesium, B vitamins, iron, and essential fats that support neurotransmission and motor coordination; and supporting gut health, mitochondrial energy, and detox pathways so the body can process and recover more effectively.

When the body’s foundation is strengthened, therapies that target speech and movement often become more effective—because the system they’re working on is more responsive.


What Progress Can Look Like

Progress often starts subtly. Parents might notice that transitions become smoother, gestures or attempts at speech appear more often, or their child seems more organized in movement. Over time, as toxic burden is reduced and deficiencies are corrected, speech and communication can begin to emerge or strengthen.

This isn’t about quick fixes—it’s about allowing the body’s natural capacity for healing to unfold. When we support the body and remove obstacles, the brain and nervous system often respond with new levels of clarity and coordination.


Bodies have a natural propensity toward healing. When we remove obstacles and offer the right kind of support, that built-in wisdom has room to do its work. This process isn’t about changing who your child is—it’s about creating the conditions where their strengths can shine.


Supporting speech and motor development through a functional, root-cause approach—helping parents understand the ‘whys’ behind apraxia and speech delay

References

Take the next small step toward your child’s healing.
Together, we can explore the whys behind your child’s speech and motor challenges, uncover possible contributing factors, and create a clear, supportive roadmap—visit-ready labs, smart questions for your clinician, and simple actions that fit real family life.

Leucovorin and Folate Pathways in Autism

(Why this therapy may help — and why it’s only one part of the whole picture)

Why Folate Matters for the Brain

Folate—also known as vitamin B9—is essential for brain development, neurotransmitter production, and detoxification. It supports processes like methylation and DNA repair that help the brain grow and function well.

But in some children on the autism spectrum, folate has trouble getting into the brain where it’s needed most. Even when blood tests show normal folate levels, the transport mechanism that moves folate across the blood–brain barrier can be blocked.

This is called Cerebral Folate Deficiency (CFD). Often, it’s linked to folate receptor alpha autoantibodies (FRAAs)—immune proteins that block the receptor responsible for carrying folate into the brain.

When this happens, kids may experience language delays, irritability, fatigue, or developmental plateaus that don’t improve with diet or therapy alone. In a functional medicine framework, this is one of many possible “root causes” we explore when progress feels stuck.


What Leucovorin Is—and How It Works

Leucovorin (folinic acid) is an active form of folate that can bypass the blocked receptor and still reach the brain.

While standard folic acid depends on the folate receptor α (FRα) to cross into the central nervous system, leucovorin uses an alternate pathway—the reduced folate carrier (RFC)—to deliver active folate directly to where it’s needed.

Once in the brain, leucovorin supports the same vital processes as natural folate: methylation, neurotransmitter balance, and mitochondrial function.

This is what makes it different from over-the-counter folic acid supplements. For children with FRAAs or other transport problems, leucovorin can sometimes “open a different door” and restore function that was otherwise blocked.


What Dr. Richard Frye’s Research Shows

Dr. Richard E. Frye, a pediatric neurologist and researcher, has published multiple studies exploring folate metabolism in autism. His work shows:

  • High rates of FRAA positivity (around 70 %) in children with autism.
  • Improved verbal communication and language development in FRAA-positive children treated with folinic acid.
  • Better social engagement and reduced irritability in several studies.
  • Dose-dependent effects: those with higher antibody levels often show stronger responses.
  • Good safety profile: side effects are generally mild and temporary (agitation, sleep changes, or headaches).

In other words, leucovorin appears to help when a clear folate-transport issue is identified—and when it’s introduced thoughtfully, as part of a broader plan.


Why It’s Not the Whole Picture

Folinic acid can make a big difference—but only if the rest of the system can support that change.

Folate metabolism is connected to everything from gut health to mitochondrial energy, detox pathways, and sleep. If those areas are still under strain, leucovorin alone may only move things partway.

Functional medicine focuses on strengthening these foundations so that targeted therapies like leucovorin can work more effectively.
That means also looking at:

  • A nutrient-dense, anti-inflammatory diet
  • A healthy gut and balanced microbiome
  • Adequate mitochondrial and detox support
  • Quality sleep and stress regulation
  • Coordinated supplement and medication routines

When these systems are supported, we tend to see steadier, longer-lasting improvements—speech that continues to build, behavior that stabilizes, and energy that feels more consistent.


Testing and Clinical Considerations

If a child’s history or symptoms suggest a possible folate-transport issue, a physician can order FRAA testing (and sometimes tests for soluble folate-binding proteins).

When results confirm an issue, leucovorin may be prescribed under medical supervision. Doses vary, but all studies emphasize close monitoring and gradual introduction.

Families should never start this on their own. It’s best used as part of a coordinated plan with a clinician who understands neurometabolic or functional medicine approaches.


A Functional Medicine Lens

In functional medicine, we rarely look for a single “answer.”
We look for patterns—nutrient pathways that need support, inflammation that needs calming, and systems that need connection.

Leucovorin can be a powerful tool for some children, especially those with confirmed folate receptor antibodies, but it’s one piece of a much larger puzzle. When we zoom out and build a foundation that supports methylation, detox, sleep, and digestion, the body can finally use these targeted interventions the way they’re intended.


Your Family’s Roadmap to Healing

If you’ve heard about leucovorin or FRAA testing and aren’t sure if it fits your child’s picture, I can help you sort through it.
Together, we can:

  • Understand what testing might be appropriate
  • Prepare visit-ready labs and questions for your clinician
  • Translate complex recommendations into clear, doable steps
  • Build the foundations that make biomedical interventions more effective

You don’t have to figure this out alone.
Step by step, we can build a roadmap that helps your child’s body work better—so therapies like leucovorin can make the difference they’re meant to.

Leucovorin (folinic acid) can bypass a blocked folate receptor to support folate transport into the brain — an important step in addressing cerebral folate deficiency seen in some children with autism.

References:

  1. Frye R.E. et al. Folinic acid improves verbal communication in children with autism spectrum disorder and language impairment: a randomized double-blind placebo-controlled trial. Mol Psychiatry (2016)
  2. Rossignol D.A., Frye R.E. Folinic acid in autism spectrum disorder: a systematic review and meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry (2021)
  3. Frye R.E. et al. Biomarker associations and clinical response to folinic acid in autism spectrum disorder. Front Neurosci (2024)

Preparing for Your First Functional Medicine Visit

How to arrive with clarity, confidence, and visit-ready data

If you’ve decided to explore functional medicine for autism, you’ve likely done a lot of research—and felt both hopeful and overwhelmed. The first appointment is a big step, and with thoughtful preparation, you can make it far more productive—and even save money by showing up with labs in hand at your very first visit.

Why preparation matters in functional medicine for autism

Functional medicine takes a deep look at the why behind symptoms. When you arrive with organized notes, relevant lab results, and clear questions, your clinician can connect dots faster, skip unnecessary testing, and focus your time where it matters most. This preparation not only improves outcomes but makes the most of your family’s investment of time and energy.

Show up with “visit-ready” labs

One of the most effective ways to make your first appointment count is to arrive with foundational labs already completed. Together, we can choose the right starting tests to give your provider insight into gut health, nutrient balance, detoxification, inflammation, and other key systems often explored in functional medicine for autism.

By arriving with this data in hand, your clinician can interpret results immediately instead of spending your first visit deciding what to order. That often means fewer follow-up appointments, faster clarity, and meaningful savings in cost and time.

How I help you prepare for your first functional medicine visit

At Autism Functional Intervention Coach, I support families before—and during—their first functional medicine visit.

Together we:

  • Identify a provider whose philosophy and logistics fit your family
  • Select and order pre-visit labs so you arrive with visit-ready data
  • Organize your child’s history, symptoms, and observations
  • Prepare focused questions to keep the appointment clear and efficient
  • Translate post-visit recommendations into simple, sustainable steps

And if you’d like, I can attend your visit remotely—helping you share history and lab findings clearly, take notes, and ensure your family’s priorities are understood. Parents often say this brings relief and confidence, especially during their first experience with functional medicine for autism.

The difference preparation makes

Families who prepare this way tell me they walk into the visit feeling calm and leave feeling empowered. Instead of adding to the overwhelm, the appointment becomes a turning point—where information and action align. Providers appreciate it too—it allows them to offer personalized guidance from day one.

Take the next small step

If you’d like to feel prepared, supported, and confident before your first functional medicine appointment, I can help. Together, we’ll gather the right information, order the right labs, and make sure you arrive ready to get the most out of your investment—with me by your side (virtually) if you wish.

Your child’s healing journey through functional medicine for autism begins with clarity—and that starts before the first visit.

Ready for a clearer path?

Functional Medicine for Autism: Your Family’s Roadmap to Healing

If you’ve landed here, you’re probably one of the many parents up late, wondering if there’s one more stone to turn to ease your child’s physical or behavioral symptoms. I’m really glad you found me.

I believe the saying, “When the student is ready, the teacher appears.” My hope is that this is the start of us learning from each other—with one shared goal: helping your child move toward their full potential for healing.

Functional medicine shares that same spirit of curiosity and partnership. Instead of chasing symptoms, we look for the reasons behind them—then build a step-by-step plan you can follow. Think of it as a roadmap, one small turn at a time.

What a “root-cause” approach really means

No two children are the same, even with the same diagnosis. I look at the whole picture—how your child sleeps, eats, feels, moves, and navigates daily life—so we can spot patterns and decide what to address first. This isn’t about quick fixes; it’s about clear priorities and changes that fit your family.

What I help with

  • Find a functional-medicine provider who fits. If you don’t have one yet, I help you identify a clinician whose approach and logistics make sense for your family.
  • Order labs before the first visit. We order the labs so you can arrive with visit-ready data and a clearer view of possible whys behind your child’s symptoms.
  • Prep for the appointment. I help you outline what matters most and prepare the questions to ask, so your time with the clinician is focused and useful.
  • Turn complicated protocols into simple action. Lengthy plans become plain-language steps, simple schedules, and routines you can actually keep.
  • Work the plan together. We draft the map, then find the paths—adjusting as your child responds.

How it usually unfolds

Listen & map. You share what’s hardest and what’s helped.
Set priorities. We choose one to three focus areas that would make daily life meaningfully easier.
Design the roadmap. We translate big ideas into a simple plan.
Implement & adjust. Small steps, steady support, thoughtful revisions.

What progress can look like

Progress tends to show up in practical ways. Evenings run more smoothly and days become a bit more predictable. Transitions take less out of everyone, energy steadies, and appointments feel clearer because you know what to ask and what you’re tracking. Over time, the load feels lighter. We measure success by comfort, function, and family rhythm—not perfection.

Bodies have a natural propensity toward healing. When we remove obstacles and offer the right kind of support, that built-in wisdom has room to do its work. This process isn’t about changing who your child is—it’s about creating the conditions where their strengths can shine. The work here is to create conditions where your child can do more of what already works for them—and where your family has a clearer path forward.

Take the next small step
If you’d like a calm, practical roadmap—visit-ready labs, clear questions for your clinician, and simple actions that fit your family—I’m here to help.

I am honored for the possibility of assisting you on your family’s healing journey.